diff --git a/.github/CODEOWNERS b/.github/CODEOWNERS
index 2af7cdb5768..0510e3a8f2d 100644
--- a/.github/CODEOWNERS
+++ b/.github/CODEOWNERS
@@ -327,6 +327,7 @@ tsconfig.json @grafana/frontend-ops
 /.yarnrc.yml @grafana/frontend-ops
 /yarn.lock @grafana/frontend-ops
 /.linguirc @grafana/user-essentials
+/babel.config.json @grafana/frontend-ops
 lerna.json @grafana/frontend-ops
 /.prettierrc.js @grafana/frontend-ops
 /.eslintrc @grafana/frontend-ops
diff --git a/.github/pr-commands.json b/.github/pr-commands.json
index 7776cf4a17f..81f055a99ce 100644
--- a/.github/pr-commands.json
+++ b/.github/pr-commands.json
@@ -23,6 +23,7 @@
         "package.json",
         "tsconfig.json",
         "lerna.json",
+        ".babelrc",
         ".prettierrc.js",
         ".eslintrc",
         "**/*.mdx"
diff --git a/Dockerfile b/Dockerfile
index a5b07242ae7..69d84fba5a1 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -20,7 +20,7 @@ COPY plugins-bundled plugins-bundled
 
 RUN yarn install
 
-COPY tsconfig.json .eslintrc .editorconfig .browserslistrc .prettierrc.js .linguirc ./
+COPY tsconfig.json .eslintrc .editorconfig .browserslistrc .prettierrc.js babel.config.json .linguirc ./
 COPY public public
 COPY scripts scripts
 COPY emails emails
diff --git a/babel.config.json b/babel.config.json
new file mode 100644
index 00000000000..28e9f48eeed
--- /dev/null
+++ b/babel.config.json
@@ -0,0 +1,62 @@
+{
+  "babelrc": false,
+  // Note: order is bottom-to-top and/or right-to-left
+  "presets": [
+    [
+      "@babel/preset-env",
+      {
+        "bugfixes": true,
+        "browserslistEnv": "dev",
+        "useBuiltIns": "entry",
+        "corejs": "3.10"
+      }
+    ],
+    [
+      "@babel/preset-typescript",
+      {
+        "allowNamespaces": true,
+        "allowDeclareFields": true
+      }
+    ],
+    [
+      "@babel/preset-react",
+      {
+        "runtime": "automatic"
+      }
+    ]
+  ],
+  "plugins": [
+    [
+      "@babel/plugin-transform-typescript",
+      {
+        "allowNamespaces": true,
+        "allowDeclareFields": true
+      }
+    ],
+    // added to mitigate https://github.com/babel/babel/issues/14289
+    // package (and following line) can be removed once the issue is fixed and released
+    "@babel/plugin-proposal-class-properties",
+    ["@babel/plugin-proposal-object-rest-spread", { "loose": true }],
+    "@babel/plugin-transform-react-constant-elements",
+    "@babel/plugin-proposal-nullish-coalescing-operator",
+    "@babel/plugin-proposal-optional-chaining",
+    "@babel/plugin-syntax-dynamic-import", // needed for `() => import()` in routes.ts
+    "angularjs-annotate",
+    "macros"
+  ],
+  "env": {
+    "production": {
+      "presets": [
+        [
+          "@babel/preset-env",
+          {
+            "browserslistEnv": "production"
+          }
+        ]
+      ]
+    },
+    "hot": {
+      "plugins": ["react-refresh/babel"]
+    }
+  }
+}
diff --git a/package.json b/package.json
index 9894734e380..f8fc45190ab 100644
--- a/package.json
+++ b/package.json
@@ -84,7 +84,19 @@
     ]
   },
   "devDependencies": {
-    "@babel/runtime": "7.21.0",
+    "@babel/core": "7.20.5",
+    "@babel/plugin-proposal-class-properties": "7.18.6",
+    "@babel/plugin-proposal-nullish-coalescing-operator": "7.18.6",
+    "@babel/plugin-proposal-object-rest-spread": "7.20.2",
+    "@babel/plugin-proposal-optional-chaining": "7.20.7",
+    "@babel/plugin-syntax-dynamic-import": "7.8.3",
+    "@babel/plugin-transform-react-constant-elements": "7.20.2",
+    "@babel/plugin-transform-runtime": "7.19.6",
+    "@babel/plugin-transform-typescript": "7.20.0",
+    "@babel/preset-env": "7.20.2",
+    "@babel/preset-react": "7.18.6",
+    "@babel/preset-typescript": "7.18.6",
+    "@babel/runtime": "7.20.1",
     "@betterer/betterer": "5.4.0",
     "@betterer/cli": "5.4.0",
     "@betterer/eslint": "5.4.0",
@@ -160,6 +172,10 @@
     "@typescript-eslint/eslint-plugin": "5.42.0",
     "@typescript-eslint/parser": "5.42.0",
     "autoprefixer": "10.4.13",
+    "babel-jest": "29.3.1",
+    "babel-loader": "9.1.0",
+    "babel-plugin-angularjs-annotate": "0.10.0",
+    "babel-plugin-macros": "3.1.0",
     "blob-polyfill": "7.0.20220408",
     "browserslist": "^4.21.4",
     "chance": "^1.0.10",
@@ -226,6 +242,7 @@
     "terser-webpack-plugin": "5.3.6",
     "testing-library-selector": "0.2.1",
     "ts-jest": "29.0.3",
+    "ts-loader": "9.3.1",
     "ts-node": "10.9.1",
     "typescript": "4.8.4",
     "wait-on": "6.0.1",
diff --git a/packages/grafana-e2e/package.json b/packages/grafana-e2e/package.json
index c493e584da2..4f6ffc860c0 100644
--- a/packages/grafana-e2e/package.json
+++ b/packages/grafana-e2e/package.json
@@ -60,7 +60,7 @@
     "webpack": "5.75.0"
   },
   "dependencies": {
-    "@babel/core": "7.21.0",
+    "@babel/core": "7.20.5",
     "@babel/preset-env": "7.20.2",
     "@cypress/webpack-preprocessor": "5.17.0",
     "@grafana/e2e-selectors": "9.5.0-pre",
diff --git a/packages/grafana-ui/package.json b/packages/grafana-ui/package.json
index 0f55fa1e5a9..a5a18e9be4d 100644
--- a/packages/grafana-ui/package.json
+++ b/packages/grafana-ui/package.json
@@ -113,7 +113,7 @@
     "uuid": "9.0.0"
   },
   "devDependencies": {
-    "@babel/core": "7.21.0",
+    "@babel/core": "7.20.5",
     "@grafana/tsconfig": "^1.2.0-rc1",
     "@mdx-js/react": "1.6.22",
     "@rollup/plugin-node-resolve": "15.0.1",
diff --git a/yarn.lock b/yarn.lock
index 2442a8538c2..8c063d67e23 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -21,16 +21,6 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@ampproject/remapping@npm:^2.2.0":
-  version: 2.2.0
-  resolution: "@ampproject/remapping@npm:2.2.0"
-  dependencies:
-    "@jridgewell/gen-mapping": ^0.1.0
-    "@jridgewell/trace-mapping": ^0.3.9
-  checksum: d74d170d06468913921d72430259424b7e4c826b5a7d39ff839a29d547efb97dc577caa8ba3fb5cf023624e9af9d09651afc3d4112a45e2050328abc9b3a2292
-  languageName: node
-  linkType: hard
-
 "@babel/code-frame@npm:^7.0.0, @babel/code-frame@npm:^7.10.4, @babel/code-frame@npm:^7.12.13, @babel/code-frame@npm:^7.14.5, @babel/code-frame@npm:^7.15.8, @babel/code-frame@npm:^7.8.3":
   version: 7.15.8
   resolution: "@babel/code-frame@npm:7.15.8"
@@ -116,13 +106,6 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/compat-data@npm:^7.20.5":
-  version: 7.21.0
-  resolution: "@babel/compat-data@npm:7.21.0"
-  checksum: dbf632c532f9c75ba0be7d1dc9f6cd3582501af52f10a6b90415d634ec5878735bd46064c91673b10317af94d4cc99c4da5bd9d955978cdccb7905fc33291e4d
-  languageName: node
-  linkType: hard
-
 "@babel/core@npm:7.12.9":
   version: 7.12.9
   resolution: "@babel/core@npm:7.12.9"
@@ -170,26 +153,26 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/core@npm:7.21.0":
-  version: 7.21.0
-  resolution: "@babel/core@npm:7.21.0"
+"@babel/core@npm:7.20.5":
+  version: 7.20.5
+  resolution: "@babel/core@npm:7.20.5"
   dependencies:
-    "@ampproject/remapping": ^2.2.0
+    "@ampproject/remapping": ^2.1.0
     "@babel/code-frame": ^7.18.6
-    "@babel/generator": ^7.21.0
-    "@babel/helper-compilation-targets": ^7.20.7
-    "@babel/helper-module-transforms": ^7.21.0
-    "@babel/helpers": ^7.21.0
-    "@babel/parser": ^7.21.0
-    "@babel/template": ^7.20.7
-    "@babel/traverse": ^7.21.0
-    "@babel/types": ^7.21.0
+    "@babel/generator": ^7.20.5
+    "@babel/helper-compilation-targets": ^7.20.0
+    "@babel/helper-module-transforms": ^7.20.2
+    "@babel/helpers": ^7.20.5
+    "@babel/parser": ^7.20.5
+    "@babel/template": ^7.18.10
+    "@babel/traverse": ^7.20.5
+    "@babel/types": ^7.20.5
     convert-source-map: ^1.7.0
     debug: ^4.1.0
     gensync: ^1.0.0-beta.2
-    json5: ^2.2.2
+    json5: ^2.2.1
     semver: ^6.3.0
-  checksum: 357f4dd3638861ceebf6d95ff49ad8b902065ee8b7b352621deed5666c2a6d702a48ca7254dba23ecae2a0afb67d20f90db7dd645c3b75e35e72ad9776c671aa
+  checksum: 9547f1e6364bc58c3621e3b17ec17f0d034ff159e5a520091d9381608d40af3be4042dd27c20ad7d3e938422d75850ac56a3758d6801d65df701557af4bd244b
   languageName: node
   linkType: hard
 
@@ -407,15 +390,14 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/generator@npm:^7.21.0, @babel/generator@npm:^7.21.1":
-  version: 7.21.1
-  resolution: "@babel/generator@npm:7.21.1"
+"@babel/generator@npm:^7.20.5":
+  version: 7.20.5
+  resolution: "@babel/generator@npm:7.20.5"
   dependencies:
-    "@babel/types": ^7.21.0
+    "@babel/types": ^7.20.5
     "@jridgewell/gen-mapping": ^0.3.2
-    "@jridgewell/trace-mapping": ^0.3.17
     jsesc: ^2.5.1
-  checksum: 69085a211ff91a7a608ee3f86e6fcb9cf5e724b756d792a713b0c328a671cd3e423e1ef1b12533f366baba0616caffe0a7ba9d328727eab484de5961badbef00
+  checksum: 31c10d1e122f08cf755a24bd6f5d197f47eceba03f1133759687d00ab72d210e60ba4011da42f368b6e9fa85cbfda7dc4adb9889c2c20cc5c34bb2d57c1deab7
   languageName: node
   linkType: hard
 
@@ -559,21 +541,6 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/helper-compilation-targets@npm:^7.20.7":
-  version: 7.20.7
-  resolution: "@babel/helper-compilation-targets@npm:7.20.7"
-  dependencies:
-    "@babel/compat-data": ^7.20.5
-    "@babel/helper-validator-option": ^7.18.6
-    browserslist: ^4.21.3
-    lru-cache: ^5.1.1
-    semver: ^6.3.0
-  peerDependencies:
-    "@babel/core": ^7.0.0
-  checksum: 8c32c873ba86e2e1805b30e0807abd07188acbe00ebb97576f0b09061cc65007f1312b589eccb4349c5a8c7f8bb9f2ab199d41da7030bf103d9f347dcd3a3cf4
-  languageName: node
-  linkType: hard
-
 "@babel/helper-create-class-features-plugin@npm:^7.18.6":
   version: 7.18.6
   resolution: "@babel/helper-create-class-features-plugin@npm:7.18.6"
@@ -833,16 +800,6 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/helper-function-name@npm:^7.21.0":
-  version: 7.21.0
-  resolution: "@babel/helper-function-name@npm:7.21.0"
-  dependencies:
-    "@babel/template": ^7.20.7
-    "@babel/types": ^7.21.0
-  checksum: d63e63c3e0e3e8b3138fa47b0cd321148a300ef12b8ee951196994dcd2a492cc708aeda94c2c53759a5c9177fffaac0fd8778791286746f72a000976968daf4e
-  languageName: node
-  linkType: hard
-
 "@babel/helper-get-function-arity@npm:^7.15.4":
   version: 7.15.4
   resolution: "@babel/helper-get-function-arity@npm:7.15.4"
@@ -1081,19 +1038,19 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/helper-module-transforms@npm:^7.21.0":
-  version: 7.21.2
-  resolution: "@babel/helper-module-transforms@npm:7.21.2"
+"@babel/helper-module-transforms@npm:^7.20.2":
+  version: 7.20.2
+  resolution: "@babel/helper-module-transforms@npm:7.20.2"
   dependencies:
     "@babel/helper-environment-visitor": ^7.18.9
     "@babel/helper-module-imports": ^7.18.6
     "@babel/helper-simple-access": ^7.20.2
     "@babel/helper-split-export-declaration": ^7.18.6
     "@babel/helper-validator-identifier": ^7.19.1
-    "@babel/template": ^7.20.7
-    "@babel/traverse": ^7.21.2
-    "@babel/types": ^7.21.2
-  checksum: 8a1c129a4f90bdf97d8b6e7861732c9580f48f877aaaafbc376ce2482febebcb8daaa1de8bc91676d12886487603f8c62a44f9e90ee76d6cac7f9225b26a49e1
+    "@babel/template": ^7.18.10
+    "@babel/traverse": ^7.20.1
+    "@babel/types": ^7.20.2
+  checksum: 33a60ca115f6fce2c9d98e2a2e5649498aa7b23e2ae3c18745d7a021487708fc311458c33542f299387a0da168afccba94116e077f2cce49ae9e5ab83399e8a2
   languageName: node
   linkType: hard
 
@@ -1301,6 +1258,15 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@babel/helper-skip-transparent-expression-wrappers@npm:^7.20.0":
+  version: 7.20.0
+  resolution: "@babel/helper-skip-transparent-expression-wrappers@npm:7.20.0"
+  dependencies:
+    "@babel/types": ^7.20.0
+  checksum: 34da8c832d1c8a546e45d5c1d59755459ffe43629436707079989599b91e8c19e50e73af7a4bd09c95402d389266731b0d9c5f69e372d8ebd3a709c05c80d7dd
+  languageName: node
+  linkType: hard
+
 "@babel/helper-split-export-declaration@npm:^7.15.4":
   version: 7.15.4
   resolution: "@babel/helper-split-export-declaration@npm:7.15.4"
@@ -1478,14 +1444,14 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/helpers@npm:^7.21.0":
-  version: 7.21.0
-  resolution: "@babel/helpers@npm:7.21.0"
+"@babel/helpers@npm:^7.20.5":
+  version: 7.20.6
+  resolution: "@babel/helpers@npm:7.20.6"
   dependencies:
-    "@babel/template": ^7.20.7
-    "@babel/traverse": ^7.21.0
-    "@babel/types": ^7.21.0
-  checksum: 9370dad2bb665c551869a08ac87c8bdafad53dbcdce1f5c5d498f51811456a3c005d9857562715151a0f00b2e912ac8d89f56574f837b5689f5f5072221cdf54
+    "@babel/template": ^7.18.10
+    "@babel/traverse": ^7.20.5
+    "@babel/types": ^7.20.5
+  checksum: f03ec6eb2bf8dc7cdfe2569ee421fd9ba6c7bac6c862d90b608ccdd80281ebe858bc56ca175fc92b3ac50f63126b66bbd5ec86f9f361729289a20054518f1ac5
   languageName: node
   linkType: hard
 
@@ -1614,12 +1580,12 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/parser@npm:^7.20.7, @babel/parser@npm:^7.21.0, @babel/parser@npm:^7.21.2":
-  version: 7.21.2
-  resolution: "@babel/parser@npm:7.21.2"
+"@babel/parser@npm:^7.20.5":
+  version: 7.20.5
+  resolution: "@babel/parser@npm:7.20.5"
   bin:
     parser: ./bin/babel-parser.js
-  checksum: e2b89de2c63d4cdd2cafeaea34f389bba729727eec7a8728f736bc472a59396059e3e9fe322c9bed8fd126d201fb609712949dc8783f4cae4806acd9a73da6ff
+  checksum: e8d514ce0aa74d56725bd102919a49fa367afef9cd8208cf52f670f54b061c4672f51b4b7980058ab1f5fe73615fe4dc90720ab47bbcebae07ad08d667eda318
   languageName: node
   linkType: hard
 
@@ -1841,6 +1807,21 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@babel/plugin-proposal-object-rest-spread@npm:7.20.2, @babel/plugin-proposal-object-rest-spread@npm:^7.20.2":
+  version: 7.20.2
+  resolution: "@babel/plugin-proposal-object-rest-spread@npm:7.20.2"
+  dependencies:
+    "@babel/compat-data": ^7.20.1
+    "@babel/helper-compilation-targets": ^7.20.0
+    "@babel/helper-plugin-utils": ^7.20.2
+    "@babel/plugin-syntax-object-rest-spread": ^7.8.3
+    "@babel/plugin-transform-parameters": ^7.20.1
+  peerDependencies:
+    "@babel/core": ^7.0.0-0
+  checksum: 9764d1a4735fcd384fdb9b6c6ccb20d1bea2f88f648640d26ce5d9cd5880ce1e389d2f852d7bea7e86ff343726225dc16e1deb92c7b3dc5c5721ed905a602318
+  languageName: node
+  linkType: hard
+
 "@babel/plugin-proposal-object-rest-spread@npm:^7.12.1, @babel/plugin-proposal-object-rest-spread@npm:^7.19.4":
   version: 7.19.4
   resolution: "@babel/plugin-proposal-object-rest-spread@npm:7.19.4"
@@ -1856,21 +1837,6 @@ __metadata:
   languageName: node
   linkType: hard
 
-"@babel/plugin-proposal-object-rest-spread@npm:^7.20.2":
-  version: 7.20.2
-  resolution: "@babel/plugin-proposal-object-rest-spread@npm:7.20.2"
-  dependencies:
-    "@babel/compat-data": ^7.20.1
-    "@babel/helper-compilation-targets": ^7.20.0
-    "@babel/helper-plugin-utils": ^7.20.2
-    "@babel/plugin-syntax-object-rest-spread": ^7.8.3
-    "@babel/plugin-transform-parameters": ^7.20.1
-  peerDependencies:
-    "@babel/core": ^7.0.0-0
-  checksum: 9764d1a4735fcd384fdb9b6c6ccb20d1bea2f88f648640d26ce5d9cd5880ce1e389d2f852d7bea7e86ff343726225dc16e1deb92c7b3dc5c5721ed905a602318
-  languageName: node
-  linkType: hard
-
 "@babel/plugin-proposal-optional-catch-binding@npm:^7.18.6":
   version: 7.18.6
   resolution: "@babel/plugin-proposal-optional-catch-binding@npm:7.18.6"
@@ -1896,6 +1862,19 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@babel/plugin-proposal-optional-chaining@npm:7.20.7":
+  version: 7.20.7
+  resolution: "@babel/plugin-proposal-optional-chaining@npm:7.20.7"
+  dependencies:
+    "@babel/helper-plugin-utils": ^7.20.2
+    "@babel/helper-skip-transparent-expression-wrappers": ^7.20.0
+    "@babel/plugin-syntax-optional-chaining": ^7.8.3
+  peerDependencies:
+    "@babel/core": ^7.0.0-0
+  checksum: 274b8932335bd064ca24cf1a4da2b2c20c92726d4bfa8b0cb5023857479b8481feef33505c16650c7b9239334e5c6959babc924816324c4cf223dd91c7ca79bc
+  languageName: node
+  linkType: hard
+
 "@babel/plugin-proposal-private-methods@npm:^7.12.1, @babel/plugin-proposal-private-methods@npm:^7.18.6":
   version: 7.18.6
   resolution: "@babel/plugin-proposal-private-methods@npm:7.18.6"
@@ -2221,6 +2200,17 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@babel/plugin-syntax-typescript@npm:^7.20.0":
+  version: 7.20.0
+  resolution: "@babel/plugin-syntax-typescript@npm:7.20.0"
+  dependencies:
+    "@babel/helper-plugin-utils": ^7.19.0
+  peerDependencies:
+    "@babel/core": ^7.0.0-0
+  checksum: 6189c0b5c32ba3c9a80a42338bd50719d783b20ef29b853d4f03929e971913d3cefd80184e924ae98ad6db09080be8fe6f1ffde9a6db8972523234f0274d36f7
+  languageName: node
+  linkType: hard
+
 "@babel/plugin-syntax-typescript@npm:^7.7.2":
   version: 7.16.0
   resolution: "@babel/plugin-syntax-typescript@npm:7.16.0"
@@ -2704,6 +2694,17 @@ __metadata:
   languageName: node
   linkType: hard
 
+"@babel/plugin-transform-react-constant-elements@npm:7.20.2":
+  version: 7.20.2
+  resolution: "@babel/plugin-transform-react-constant-elements@npm:7.20.2"
+  dependencies:
+    "@babel/helper-plugin-utils": ^7.20.2
+  peerDependencies:
+    "@babel/core": ^7.0.0-0
+  checksum: 7b041b726e7c14b8c26a0dd240defac5f93a1f449371c6bdc5e6b46d581211300cc1a79da4140bdf20347f49e175dcb4f469812399206864024d1fdc81171193
+  languageName: node
+  linkType: hard
+
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   version: 7.18.6
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   resolution: "grafana@workspace:."
   dependencies:
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+    "@babel/core": 7.20.5
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     "@betterer/eslint": 5.4.0
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     app: "link:./public/app"
     autoprefixer: 10.4.13
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     blob-polyfill: 7.0.20220408
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